A low-dose OC with

an innovative 4-phasic

dosing regimen²

For pregnancy prevention and the treatment of heavy menstrual bleeding (HMB) in women without organic pathology who choose to use an oral contraceptive (OC) as their method of contraception¹

Natazia^® is the only available low-dose OC with estradiol valerate (E₂V) as part of a 28-day regimen^1,3

Breaking down the

4 phases of Natazia

Phase 1 (Days 1-2) Encourages endometrial buildup with an initial 3-mg dose of E₂V²

Phase 2 (Days 3-7) Slows endometrial growth by introducing a low dose of dienogest (DNG) (2 mg), while reducing E₂V (2 mg)²

Phase 3 (Days 8-24) Stabilizes the endometrium by raising the DNG level (3 mg)^2,4

Phase 4 (Days 25-26 and Days 27-28) Promotes a controlled menses by ending with a short interval of further-reduced E₂V (1 mg) only, followed by a 2-day washout^2,5,6

See Natazia Pregnancy Prevention Data >>

Important Safety Information

More Important Safety Information More Important Safety Information

Women over 35 years old who smoke should not use Natazia. Smoking increases the risk of serious cardiovascular side effects from Natazia use. This risk increases with age and the number of cigarettes smoked.