References

 

  1. FDA approves Natazia for heavy menstrual bleeding [press release]. Wayne, NJ: Bayer HealthCare Pharmaceuticals Inc; March 14, 2012. https://www.drugs.com/newdrugs/u-s-fda-approves-first-only-oral-contraceptive-demonstrated-heavy-menstrual-bleeding-hmb-3150.html. Accessed March 29, 2019. 
  2. Endrikat J, Parke S, Trummer D, Schmidt W, Duijkers I, Klipping C. Ovulation inhibition with four variations of a four-phasic estradiol valerate/dienogest combined oral contraceptive: results of two prospective, randomized, open-label studies. Contraception. 2008;78(3):218-225.
  3. Natazia—a new oral contraceptive. Med Lett Drugs Ther. 2010;52(1346):71-72.
  4. Rafie S, Borgelt L, Koepf ER, Temple-Cooper ME, Lehman KJ. Novel oral contraceptive for heavy menstrual bleeding: estradiol valerate and dienogest. Int J Womens Health. 2013;5:313-321.
  5. Nelson A. New low-dose, extended-cycle pills with levonorgestrel and ethinyl estradiol: an evolutionary step in birth control. Int J Womens Health. 2010;2:99-106.
  6. Mayo Clinic. Birth control pill FAQ: benefits, risks and choices. https://www.mayoclinic.org/healthy-lifestyle/birth-control/in-depth/birth-control-pill/art-20045136. Updated May 25, 2019. Accessed August 13, 2019.
  7. Ahrendt H-J, Makalová D, Parke S, Mellinger U, Mansour D. Bleeding pattern and cycle control with an estradiol-based oral contraceptive: a seven-cycle, randomized comparative trial of estradiol valerate/dienogest and ethinyl estradiol/levonorgestrel. Contraception. 2009;80(5):436-444.
  8. Data on file. CSR A35644. Bayer HealthCare Pharmaceuticals Inc; Whippany, NJ. 
  9. Fraser IS, Römer T, Parke S, et al. Effective treatment of heavy and/or prolonged menstrual bleeding with an oral contraceptive containing estradiol valerate and dienogest: a randomized, double-blind phase III trial. Hum Reprod. 2011;26(10):2698-2708.
  10. Jensen JT, Parke S, Mellinger U, Machlitt A, Fraser IS. Effective treatment of heavy menstrual bleeding with estradiol valerate and dienogest: a randomized controlled trial. Obstet Gynecol. 2011;117(4):777-787.